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KMID : 1160120150040020023
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Journal of the Korean Society of Beauty Cultural Arts
2015 Volume.4 No. 2 p.23 ~ p.30
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Study on Cosmeceutical Activities of Paeonia japonica Extracts
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Kim Mi-Yeon
Yoon Bok-Yeon
Ko Kyoung-Sook
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Abstract
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In this study, we investigated the possibility of Paeonia japonica extract as a cosmetic ingredient and evaluate the antioxidant activity, anti-inflammatory, cytotoxic efficacy of those of decursiva extract. As a result, DPPH radical scavenging activity, the results similarly had scavenging can check this increased ABTS radical scavenging ability measurement results showed a low antioxidant activity compared to the positive control group and dose-dependently increased the radical scavenging activity with increasing concentration of Paeonia japonica extract It showed. A polyphenol and flavonoid content was 125.1 ± 0.005 ㎎ / g, 136.1 ± 0.007 ㎎ / g content of each. And a result Paeonia japonica measure the survival rate of cells using Raw 264.7 cell in order to determine the cytotoxic or absence of Paeonia japonica extract extract showed a result rather no cytotoxicity at a low concentration. As a result the final increase in the concentration of NO production inhibitory ability Paeonia japonica extract examined for the Raw 264.7 cell induced by LPS The results showed that NO production is reduced. As seen in the above results, that the active ingredient of the brief Paeonia japonica ethanol extract results to show the high potential as a functional material of cosmetics or the anti-inflammatory and antioxidant expected to application as a natural effect of the cosmetic material having a non-toxic.
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KEYWORD
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Cosmeceutical activities, Antioxidants, Antiinflammatory, Paeonia japonica
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